Heavy smoker (≥15 cigarettes in 24-hr period) One 25-mg patch/16 hr daily for 1st 8 wk, then one 15-mg patch/16 hr daily for the next 2 wk & one 10-mg patch/16 hr daily for the final 2 wk. Light smoker (<15 cigarettes in 24-hr period) One 15-mg patch/16 hr daily for 1st 8 wk then one 10-mg patch/16 hr daily for the final 4 wk.
Discontinue use if any symptoms of nicotine excess occur. Recent stroke, MI, unstable angina, cardiac arrhythmia, CABG & angioplasty or uncontrolled HTN. Diabetes; overactive thyroid gland, phaeochromocytoma; stomach ulcer, oesophagitis; history of epilepsy & seizures. Remove patch prior to MRI procedures. Not recommended to use beyond 6 mth. Moderate to severe hepatic &/or severe renal impairment. Pregnancy. Avoid use during lactation. Not to be used in childn & adolescent <18 yr.